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Domino living donor liver transplantation of familial amyloid polyneuropathy patient - A case report.
- Source :
-
Anesthesia and pain medicine [Anesth Pain Med (Seoul)] 2020 Oct 30; Vol. 15 (4), pp. 472-477. Date of Electronic Publication: 2020 Oct 14. - Publication Year :
- 2020
-
Abstract
- Background: Familial amyloid polyneuropathy (FAP) is caused by mutation in a gene transcribing transport protein produced mainly by the liver. Liver transplantation is required to stop FAP progression, but the pathology causes anesthetic management challenges.<br />Case: We report a case of domino living donor liver transplantation in an FAP patient. No intraoperative events occurred; however, during postoperative day 1 in the intensive care unit (ICU), the FAP patient underwent multiple cardiopulmonary resuscitation (CPR) sessions due to pulseless electrical activity following a sudden drop in blood pressure and ventricular tachycardia. Despite ICU management, the patient died after the third CPR session.<br />Conclusions: Various anesthetic management techniques should be considered for FAP patients. Anesthetic management was carefully assessed with the use of isoflurane, isoproterenol, and an external patch. The cause of deterioration in the ICU is unclear, but further investigation is needed to prevent and better manage postoperative morbidity and mortality.<br />Competing Interests: CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported.<br /> (Copyright © the Korean Society of Anesthesiologists, 2020.)
Details
- Language :
- English
- ISSN :
- 1975-5171
- Volume :
- 15
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Anesthesia and pain medicine
- Publication Type :
- Report
- Accession number :
- 33329851
- Full Text :
- https://doi.org/10.17085/apm.20059