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Statistical field theory of the transmission of nerve impulses.

Authors :
Zangari Del Balzo G
Source :
Theoretical biology & medical modelling [Theor Biol Med Model] 2021 Jan 06; Vol. 18 (1), pp. 1. Date of Electronic Publication: 2021 Jan 06.
Publication Year :
2021

Abstract

Background: Stochastic processes leading voltage-gated ion channel dynamics on the nerve cell membrane are a sufficient condition to describe membrane conductance through statistical mechanics of disordered and complex systems.<br />Results: Voltage-gated ion channels in the nerve cell membrane are described by the Ising model. Stochastic circuit elements called "Ising Neural Machines" are introduced. Action potentials are described as quasi-particles of a statistical field theory for the Ising system.<br />Conclusions: The particle description of action potentials is a new point of view and a powerful tool to describe the generation and propagation of nerve impulses, especially when classical electrophysiological models break down. The particle description of action potentials allows us to develop a new generation of devices to study neurodegenerative and demyelinating diseases as Multiple Sclerosis and Alzheimer's disease, even integrated by connectomes. It is also suitable for the study of complex networks, quantum computing, artificial intelligence, machine and deep learning, cryptography, ultra-fast lines for entanglement experiments and many other applications of medical, physical and engineering interest.

Details

Language :
English
ISSN :
1742-4682
Volume :
18
Issue :
1
Database :
MEDLINE
Journal :
Theoretical biology & medical modelling
Publication Type :
Academic Journal
Accession number :
33407639
Full Text :
https://doi.org/10.1186/s12976-020-00132-9