[Stereotactic body radiotherapy for locally advanced pancreatic cancer: A systemic review].

Authors :: Tonneau M
Lacornerie T
Mirabel X
Pasquier D
Source :: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2021 May; Vol. 25 (3), pp. 283-295. Date of Electronic Publication: 2021 Jan 07.
Publication Year :: 2021
Abstract: Stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) is an emerging treatment option. Most studies showed local control of approximately 75% with no evidence of improved overall survival. Gastrointestinal toxicities could be significant, ranging up to 22% for acute toxicities≥grade 3+ and 44% for late toxicities≥grade 3+. Currently, no standardized guidelines for treatment and management scheme. We conducted a systemic review of published prospective and retrospective trials to evaluate the efficacy, safety, technical data, and discuss future directions.<br /> (Copyright © 2021 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.)

Subjects :: Chemoradiotherapy
Clinical Trials, Phase II as Topic
Humans
Pancreatic Neoplasms mortality
Pancreatic Neoplasms pathology
Pancreatic Neoplasms therapy
Prospective Studies
Radiosurgery adverse effects
Radiosurgery mortality
Retrospective Studies
Treatment Outcome
Pancreatic Neoplasms radiotherapy
Radiosurgery methods

Language :: French
ISSN :: 1769-6658
Volume :: 25
Issue :: 3
Database :: MEDLINE
Journal :: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Publication Type :: Academic Journal
Accession number :: 33423968
Full Text :: https://doi.org/10.1016/j.canrad.2020.08.047

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