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Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department: A retrospective cohort study.

Authors :
Kim KJ
Min JH
Yoo I
Kim SW
Lee J
Ryu S
You YH
Park JS
Jeong WJ
Cho YC
Oh SK
In YN
Ahn HJ
Kang CS
Kyung H
Lee BK
Lee DH
Lee DH
Source :
Medicine [Medicine (Baltimore)] 2021 Jan 22; Vol. 100 (3), pp. e24290.
Publication Year :
2021

Abstract

Abstract: This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.<br />Competing Interests: The authors have no conflicts of interest to disclose.<br /> (Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)

Details

Language :
English
ISSN :
1536-5964
Volume :
100
Issue :
3
Database :
MEDLINE
Journal :
Medicine
Publication Type :
Academic Journal
Accession number :
33546055
Full Text :
https://doi.org/10.1097/MD.0000000000024290