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COVID-19 in patients with cancer: Risks and precautions.
- Source :
-
The American journal of emergency medicine [Am J Emerg Med] 2021 Oct; Vol. 48, pp. 357-360. Date of Electronic Publication: 2021 Jan 28. - Publication Year :
- 2021
-
Abstract
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of the coronavirus family, which causes coronavirus disease 2019 (COVID-19). The phenotype of the disease varies from asymptomatic, to a mild phenotype, through to the severe form of acute respiratory distress syndrome (ARDS), which often leads to death, especially in those with underlying diseases. It has been reported that those who suffer from cancer (especially lung cancer and hematological malignancies) are at higher risk of serious complications and death from COVID-19. Some cancer treatments such as CAR T cell therapy can produce a cytokine storm, which is also a hallmark of severe COVID-19. Therefore, patients receiving CAR T cells are at higher risk if they become infected with COVID-19, and could be treated with anti-cytokine approaches.<br />Competing Interests: Declaration of Competing Interest None<br /> (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Subjects :
- COVID-19 complications
COVID-19 immunology
Cytokine Release Syndrome immunology
Disease Susceptibility
Hematologic Neoplasms complications
Hematologic Neoplasms immunology
Hematologic Neoplasms physiopathology
Hematologic Neoplasms therapy
Humans
Immunocompromised Host
Immunotherapy, Adoptive adverse effects
Lung Neoplasms complications
Lung Neoplasms immunology
Lung Neoplasms physiopathology
Lung Neoplasms therapy
Neoplasms complications
Neoplasms immunology
Neoplasms therapy
Receptors, Chimeric Antigen
SARS-CoV-2
Severity of Illness Index
T-Lymphocytes immunology
COVID-19 physiopathology
Neoplasms physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8171
- Volume :
- 48
- Database :
- MEDLINE
- Journal :
- The American journal of emergency medicine
- Publication Type :
- Editorial & Opinion
- Accession number :
- 33546958
- Full Text :
- https://doi.org/10.1016/j.ajem.2021.01.067