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Cycad Genotoxin Methylazoxymethanol Disrupts the Brain Ubiquitin-Proteasome Pathway, Tau and α-Synuclein, as Reported in ALS-PDC.
- Source :
-
Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2021 Feb 22; Vol. 80 (3), pp. 286-288. - Publication Year :
- 2021
- Subjects :
- Animals
Humans
Mice
Amyotrophic Lateral Sclerosis chemically induced
Amyotrophic Lateral Sclerosis metabolism
Amyotrophic Lateral Sclerosis pathology
Mutagens isolation & purification
Mutagens toxicity
Parkinson Disease, Secondary chemically induced
Parkinson Disease, Secondary metabolism
Parkinson Disease, Secondary pathology
Signal Transduction drug effects
Signal Transduction physiology
alpha-Synuclein metabolism
Brain drug effects
Brain metabolism
Cycas toxicity
Methylazoxymethanol Acetate analogs & derivatives
Methylazoxymethanol Acetate isolation & purification
Methylazoxymethanol Acetate toxicity
Proteasome Endopeptidase Complex metabolism
Ubiquitin metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1554-6578
- Volume :
- 80
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of neuropathology and experimental neurology
- Publication Type :
- Report
- Accession number :
- 33550390
- Full Text :
- https://doi.org/10.1093/jnen/nlab006