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Prostatic leiomyosarcoma in a dog treated using a multimodal approach.
- Source :
-
Journal of veterinary internal medicine [J Vet Intern Med] 2021 Mar; Vol. 35 (2), pp. 1105-1110. Date of Electronic Publication: 2021 Feb 24. - Publication Year :
- 2021
-
Abstract
- Prostatic leiomyosarcoma is an uncommon tumor encountered in male dogs, with only 2 cases reported in the veterinary literature with no follow-up described. A 12-year-old male intact German Wirehaired Pointer presented for evaluation of straining to defecate and urinate. Whole body computed tomography (CT) examination identified a spherical multicavitary expansile mass arising from the prostate gland and severely obliterating the pelvic canal. Partial subcapsular prostatectomy was performed, and histological and immunohistochemical results were consistent with prostatic leiomyosarcoma. Metronomic cyclophosphamide and nonsteroidal anti-inflammatory drugs were administered as adjuvant chemotherapy. Follow-up CT 10 months later indicated no signs of recurrence or metastasis. To the best of our knowledge, this patient represents the first report of successful multidisciplinary treatment consisting of partial subcapsular prostatectomy and adjuvant chemotherapy for prostatic leiomyosarcoma in a dog. After 15 months of follow-up, the patient remained recurrence-free without metastasis.<br /> (© 2021 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC. on behalf of the American College of Veterinary Internal Medicine.)
- Subjects :
- Animals
Dogs
Male
Neoplasm Recurrence, Local veterinary
Prostatectomy veterinary
Tomography, X-Ray Computed
Dog Diseases diagnostic imaging
Dog Diseases drug therapy
Dog Diseases surgery
Leiomyosarcoma drug therapy
Leiomyosarcoma surgery
Leiomyosarcoma veterinary
Prostatic Neoplasms drug therapy
Prostatic Neoplasms surgery
Prostatic Neoplasms veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1939-1676
- Volume :
- 35
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of veterinary internal medicine
- Publication Type :
- Report
- Accession number :
- 33625746
- Full Text :
- https://doi.org/10.1111/jvim.16081