Back to Search
Start Over
Left Ventricular Assist Device Implantation in Hypertrophic and Restrictive Cardiomyopathy: A Systematic Review.
- Source :
-
ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2021 Mar 01; Vol. 67 (3), pp. 239-244. - Publication Year :
- 2021
-
Abstract
- Left ventricular assist device (LVAD) implantation in patients with advanced heart failure due to hypertrophic or restrictive cardiomyopathy (HCM/RCM) presents technical and physiologic challenges. We conducted a systematic review of observational studies to evaluate the utilization and clinical outcomes associated with LVAD implantation in patients with HCM/RCM and compared these to patients with dilated or ischemic cardiomyopathy (DCM/ICM). We searched MEDLINE, EMBASE, and Scopus from inception through May 2019 and included appropriate studies describing the use of an LVAD in patients with HCM/RCM. We identified six studies with a total of 2,766 patients with HCM/RCM and advanced heart failure, among whom 338 patients (12.2%) underwent LVAD implantation. In patients listed for transplant, the rate of LVAD implantation was significantly lower in patients with HCM/RCM compared to that in patients with DCM/ICM (4.4% vs. 18.2%, p < 0.001). Adverse clinical outcomes were significantly higher in HCM/RCM than in DCM/ICM, including operative/short-term mortality (14.0% vs. 9.0%), right ventricular failure (50.0% vs. 21.0%), infection (15.5% vs. 11.2%), bleeding (40.2% vs. 12.5%), renal failure (15.0% vs. 5.1%), stroke (5.0% vs. 2.4%), and arrhythmias (18.0% vs. 7.7%) (all p values <0.001).<br />Competing Interests: The authors have no conflicts of interest to report.<br /> (Copyright © ASAIO 2020.)
- Subjects :
- Adult
Cardiomyopathy, Restrictive complications
Cardiovascular Surgical Procedures methods
Cardiovascular Surgical Procedures mortality
Female
Heart Failure etiology
Humans
Male
Middle Aged
Observational Studies as Topic
Cardiomyopathy, Hypertrophic surgery
Cardiomyopathy, Restrictive surgery
Heart Failure surgery
Heart-Assist Devices
Subjects
Details
- Language :
- English
- ISSN :
- 1538-943X
- Volume :
- 67
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- ASAIO journal (American Society for Artificial Internal Organs : 1992)
- Publication Type :
- Academic Journal
- Accession number :
- 33627595
- Full Text :
- https://doi.org/10.1097/MAT.0000000000001238