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Potential risk for developing severe COVID-19 disease among anabolic steroid users.
- Source :
-
BMJ case reports [BMJ Case Rep] 2021 Feb 26; Vol. 14 (2). Date of Electronic Publication: 2021 Feb 26. - Publication Year :
- 2021
-
Abstract
- A severe case of COVID-19 was observed in an otherwise healthy 28-year-old man who had taken oxandrolone 40 mg/day as an anabolic steroid. The patient had been taking oxandrolone for enhanced bodybuilding 30 days prior to presenting to an outpatient clinic with COVID-19 symptoms. The patient reported that his symptoms have rapidly worsened over the course of 4 days prior to presenting at the clinic. As part of an experimental antiandrogen treatment for hyperandrogenic men suffering from COVID-19, he was administered a single 600 mg dose of the novel antiandrogen proxalutamide. Twenty-four hours after administration of this dose, marked improvement of symptoms and markers of disease severity were observed. To our knowledge, this is the first case that potentially links anabolic steroid use to COVID-19 disease severity.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Adult
Anabolic Agents administration & dosage
Disease Progression
Humans
Male
Oxandrolone administration & dosage
Performance-Enhancing Substances adverse effects
SARS-CoV-2
Severity of Illness Index
Anabolic Agents adverse effects
Androgen Antagonists administration & dosage
Oxandrolone adverse effects
Oxazoles administration & dosage
Thiohydantoins administration & dosage
COVID-19 Drug Treatment
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 14
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 33637513
- Full Text :
- https://doi.org/10.1136/bcr-2021-241572