FAPI Uptake in a Vertebral Body Fracture in a Patient With Lung Cancer: A FAPI Imaging Pitfall.

Authors :: Wu J
Liu H
Ou L
Jiang G
Zhang C
Source :: Clinical nuclear medicine [Clin Nucl Med] 2021 Jun 01; Vol. 46 (6), pp. 520-522.
Publication Year :: 2021
Abstract: Abstract: A left pulmonary nodule was identified by CT scan in a 53-year-old woman who had a car accident 10 days earlier. 18F-FDG PET/CT showed multiple FDG-avid lesions located at the left lung nodule, mediastinal lymph nodules, and L4 vertebral body. 68Ga-FAPI PET/CT was performed for further evaluation. However, 68Ga-FAPI demonstrated intense FAPI uptake in the accident-related fracture of the L4 vertebral body. This case documents that the fracture of the vertebral body may cause FAPI uptake, and nuclear clinicians evaluating 68Ga-FAPI imaging should be aware of this potential pitfall.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Artifacts
Biological Transport
Female
Fractures, Bone complications
Humans
Middle Aged
Fractures, Bone diagnostic imaging
Fractures, Bone metabolism
Lung Neoplasms complications
Lung Neoplasms diagnostic imaging
Positron Emission Tomography Computed Tomography
Quinolines metabolism
Vertebral Body injuries

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