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Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
- Source :
-
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 May 05; Vol. 41 (5), pp. 1694-1709. Date of Electronic Publication: 2021 Mar 25. - Publication Year :
- 2021
-
Abstract
- [Figure: see text].
- Subjects :
- Aged
Aged, 80 and over
Angiotensin II
Animals
Aorta, Abdominal pathology
Aortic Aneurysm, Abdominal chemically induced
Aortic Aneurysm, Abdominal enzymology
Aortic Aneurysm, Abdominal genetics
Aortic Rupture chemically induced
Aortic Rupture enzymology
Aortic Rupture genetics
Calpain genetics
Calpain metabolism
Cells, Cultured
Cytoskeleton enzymology
Cytoskeleton pathology
Dilatation, Pathologic
Disease Models, Animal
Extracellular Matrix enzymology
Extracellular Matrix pathology
Female
Humans
Male
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Rats
Receptors, LDL deficiency
Receptors, LDL genetics
Mice
Aorta, Abdominal enzymology
Aortic Aneurysm, Abdominal prevention & control
Aortic Rupture prevention & control
Calpain deficiency
Vascular Remodeling
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4636
- Volume :
- 41
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Arteriosclerosis, thrombosis, and vascular biology
- Publication Type :
- Academic Journal
- Accession number :
- 33761765
- Full Text :
- https://doi.org/10.1161/ATVBAHA.120.315546