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Complementary Role of 68Ga-Prostate-Specific Membrane Antigen and 18F-FDG PET/CT for Evaluation of Metastases and Treatment Response in Renal Cell Carcinoma.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2021 Jul 01; Vol. 46 (7), pp. 579-581. - Publication Year :
- 2021
-
Abstract
- Abstract: We present a case of clear cell renal cell carcinoma, which demonstrates complementary FDG and prostate-specific membrane antigen (PSMA) uptake on metastases in PET/CT, as an example of tumor heterogeneity. The patient had non-FDG-avid lung and bone metastases with PSMA uptake, whereas metastatic cervical and axillary lymph nodes showed vice versa, and skeletal muscle metastasis to vastus lateralis, which is an unusual region for metastasis, showed both PSMA and FDG positivity. In response assessment, mix response was detected. It seems that 68Ga-PSMA and 18F-FDG may have a complementary role in demonstration of metastasis accurately and assessment of treatment response in clear cell renal cell carcinoma.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Aged
Carcinoma, Renal Cell therapy
Gallium Isotopes
Gallium Radioisotopes
Humans
Kidney Neoplasms therapy
Male
Middle Aged
Neoplasm Metastasis
Treatment Outcome
Carcinoma, Renal Cell diagnostic imaging
Carcinoma, Renal Cell pathology
Edetic Acid analogs & derivatives
Fluorodeoxyglucose F18
Kidney Neoplasms diagnostic imaging
Kidney Neoplasms pathology
Oligopeptides
Positron Emission Tomography Computed Tomography
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 46
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 33782292
- Full Text :
- https://doi.org/10.1097/RLU.0000000000003590