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Vγ6 + γδ T cells are critical for protection against infection by Escherichia coli in mice.
- Source :
-
European journal of immunology [Eur J Immunol] 2021 Aug; Vol. 51 (8), pp. 2093-2096. Date of Electronic Publication: 2021 Apr 01. - Publication Year :
- 2021
-
Abstract
- γδ T cells producing IL-17A (γδTh17 cells) are known to be involved in peritonitis induced by Escherichia coli infection in mice. In vivo treatment with Vγ6-specific mAb (1C10-1F7) significantly hampered resolution of E. coli infection. Thus, Vγ6 <superscript>+</superscript> γδTh17 cells mainly contributed to protection against E. coli infection.<br /> (© 2021 Wiley-VCH GmbH.)
Details
- Language :
- English
- ISSN :
- 1521-4141
- Volume :
- 51
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- European journal of immunology
- Publication Type :
- Report
- Accession number :
- 33792925
- Full Text :
- https://doi.org/10.1002/eji.202049010