Metronidazole-induced encephalopathy.

Authors :: Lala VG
Bobat B
Haagensen M
Kathan P
Mahomed A
Source :: SA journal of radiology [SA J Radiol] 2021 Mar 18; Vol. 25 (1), pp. 2016. Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Metronidazole is a widely used antibacterial and antiprotozoal agent for a number of conditions. Whilst its more common gastrointestinal side effects are well known, neurotoxicity remains under-recognised. Both central and peripheral neurological side effects have been described. This report describes a case of radiologically confirmed metronidazole-induced cerebellar ataxia in a cirrhotic patient with a review of the literature. Awareness of this side effect is essential for prompt recognition as early drug withdrawal leads to resolution in the majority of cases.<br />Competing Interests: The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article.<br /> (© 2021. The Authors.)