Preliminary evaluation of a new Schistosoma Immunochromatographic Test.

Authors :: Longoni SS
Piubelli C
Perandin F
Rizzi E
Luchetta N
Degani M
Tais S
Mori A
Bisoffi Z
Source :: Acta tropica [Acta Trop] 2021 Jul; Vol. 219, pp. 105893. Date of Electronic Publication: 2021 Apr 16.
Publication Year :: 2021
Abstract: Over 90% of schistosomiasis infections occur in sub-Saharan Africa. A rapid ICT test would be a cheap and easy tool that could be used also in the field. We preliminarily evaluated the performance of a new Schistosoma black-latex based IgG-IgM ICT (Black-ICT) on serum samples. The results indicate a high sensitivity (98.0%) but the specificity depends on the application of a cut-off value that can discriminate between positive and negative samples. Considering a possible direct application of this test on blood from finger prick, the results are promising, providied that a signal intensity scale is developed, guiding the result interpretation.<br /> (Copyright © 2021. Published by Elsevier B.V.)