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Candida auris : A Quick Review on Identification, Current Treatments, and Challenges.
- Source :
-
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 25; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 25. - Publication Year :
- 2021
-
Abstract
- Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported.
- Subjects :
- Antifungal Agents chemistry
Antifungal Agents therapeutic use
Azoles pharmacology
Candida drug effects
Candidiasis microbiology
Drug Therapy, Combination
Echinocandins pharmacology
Humans
Mycology methods
Polyenes pharmacology
Treatment Failure
Antifungal Agents pharmacology
Candida isolation & purification
Candidiasis drug therapy
Drug Resistance, Fungal drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1422-0067
- Volume :
- 22
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- International journal of molecular sciences
- Publication Type :
- Academic Journal
- Accession number :
- 33922907
- Full Text :
- https://doi.org/10.3390/ijms22094470