Prevalence of thrombotic complications in children with SARS-CoV-2.

Authors :: Aguilera-Alonso D
Murias S
Martínez-de-Azagra Garde A
Soriano-Arandes A
Pareja M
Otheo E
Moraleda C
Tagarro A
Calvo C
Source :: Archives of disease in childhood [Arch Dis Child] 2021 Nov; Vol. 106 (11), pp. 1129-1132. Date of Electronic Publication: 2021 Apr 30.
Publication Year :: 2021
Abstract: Knowledge of thrombosis in children with SARS-CoV-2 is scarce. In this multicentre national cohort of children with SARS-CoV-2 involving 49 hospitals, 4 patients out of 537 infected children developed a thrombotic complication (prevalence of 0.7% (95% CI: 0.2% to 1.9%) out of the global cohort and 1.1% (95% CI: 0.3% to 2.8%) out of the hospitalised patients). We describe their characteristics and review other published paediatric cases. Three out of the four patients were adolescent girls, and only two cases had significant thrombotic risk factors. In this paediatric cohort, D-dimer value was not specific enough to predict thrombotic complications. Adolescence and previous thrombotic risk factors may be considered when initiating anticoagulant prophylaxis on children with SARS-CoV-2 disease (COVID-19).<br />Competing Interests: Competing interests: None declared.<br /> (© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)