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The effect of TGFβRI inhibition on extracellular matrix structure and stiffness in hypertrophic scar-specific fibroblast-derived matrix models.
- Source :
-
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jun 25; Vol. 559, pp. 245-251. Date of Electronic Publication: 2021 May 05. - Publication Year :
- 2021
-
Abstract
- Competing Interests: Declaration of competing interest RSR, LvH, LB, RvD, PPMZ, MLG, AEG declare that there are no conflicts of interest. NA is an employee at Optics11Life.
- Subjects :
- Biomechanical Phenomena
Collagen metabolism
Exons genetics
Gene Expression Regulation
Humans
RNA, Messenger genetics
RNA, Messenger metabolism
Receptor, Transforming Growth Factor-beta Type I metabolism
Cicatrix, Hypertrophic pathology
Extracellular Matrix pathology
Fibroblasts metabolism
Fibroblasts pathology
Receptor, Transforming Growth Factor-beta Type I antagonists & inhibitors
Subjects
Details
- Language :
- English
- ISSN :
- 1090-2104
- Volume :
- 559
- Database :
- MEDLINE
- Journal :
- Biochemical and biophysical research communications
- Publication Type :
- Academic Journal
- Accession number :
- 33964734
- Full Text :
- https://doi.org/10.1016/j.bbrc.2021.04.071