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Clinical Presentation and Management of Severe Acute Renal Failure in McArdle Disease.
- Source :
-
Clinical medicine & research [Clin Med Res] 2021 Jun; Vol. 19 (2), pp. 90-93. Date of Electronic Publication: 2021 May 13. - Publication Year :
- 2021
-
Abstract
- McArdle disease, also known as glycogen storage disease type V, is an autosomal recessive disease due to the absence of myophosphorylase activity, leading to the complete disruption of glycogen breakdown in muscles. We present a rare case of a Caucasian male, aged 26 years, who developed rhabdomyolysis-induced acute renal failure and uremic encephalopathy. Neurological examination and histopathological studies supported the diagnosis of McArdle disease. The severity of his symptoms necessitated urgent hemodialysis, upon which the patient reported improvement in status. Acute renal failure in McArdle disease usually resolves with supportive treatment and maintenance of regular physical activity. Nevertheless, in more severe cases, intensive care with urgent hemodialysis may be needed. A multidisciplinary approach is necessary for the adequate management of similar cases.<br /> (© 2021 Marshfield Clinic Health System.)
- Subjects :
- Humans
Male
Renal Dialysis
Acute Kidney Injury diagnosis
Acute Kidney Injury etiology
Acute Kidney Injury therapy
Glycogen Storage Disease Type V complications
Glycogen Storage Disease Type V diagnosis
Glycogen Storage Disease Type V therapy
Rhabdomyolysis diagnosis
Rhabdomyolysis etiology
Rhabdomyolysis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1554-6179
- Volume :
- 19
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical medicine & research
- Publication Type :
- Academic Journal
- Accession number :
- 33985978
- Full Text :
- https://doi.org/10.3121/cmr.2021.1641