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Composite hemangioendothelioma of the spleen with multiple metastases: CT findings and review of the literature.
- Source :
-
Medicine [Medicine (Baltimore)] 2021 May 28; Vol. 100 (21), pp. e25846. - Publication Year :
- 2021
-
Abstract
- Abstract: Composite hemangioendothelioma (CHE) is a rare vascular neoplasm of intermediate malignant potential. Only 52 cases have been reported in the English literature, and one case previously reported occurred in the spleen. The purpose of our study was to report a 65-year-old man diagnosed as CHE primary arising from the spleen with multiple metastases.Clinical and imaging features, laboratory tests, and pathological results about CHE were described in detail in this study.The patient presented with multiple lesions in bilateral lungs and spleen that had been incidentally detected by computed tomography (CT). Except for thrombocytopenia, other laboratory tests were not significant. The CT scan of the abdomen revealed multiple round-like and irregularly mixed density masses with unclear borders in enlarged spleen. And contrast enhancement showed mild heterogeneous enhancement. CT scan also showed widespread liver, ribs, lungs, and vertebral bodies metastases. This diagnosis was confirmed by histopathological examination. The patient underwent splenectomy and still survives with tumors after six months followed-up.Due to the lack of specificity of clinical features and laboratory tests, it is necessary to combine imaging features and pathological findings to make a correct diagnosis.<br />Competing Interests: The authors have no conflicts of interest to disclose.<br /> (Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Aged
Hemangioendothelioma secondary
Hemangioendothelioma surgery
Humans
Male
Neoplasms, Complex and Mixed secondary
Neoplasms, Complex and Mixed surgery
Spleen diagnostic imaging
Splenectomy
Splenic Neoplasms pathology
Splenic Neoplasms surgery
Tomography, X-Ray Computed
Treatment Outcome
Hemangioendothelioma diagnosis
Neoplasms, Complex and Mixed diagnosis
Spleen pathology
Splenic Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 100
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 34032697
- Full Text :
- https://doi.org/10.1097/MD.0000000000025846