Back to Search
Start Over
An induced pluripotent stem cell line (EHTJUi003-A) generated from a neonate with c.1377delC mutation in the gene MYBPC3 causing hypertrophic cardiomyopathy.
- Source :
-
Stem cell research [Stem Cell Res] 2021 May; Vol. 53, pp. 102328. Date of Electronic Publication: 2021 Apr 12. - Publication Year :
- 2021
-
Abstract
- Hypertrophic cardiomyopathy (HCM) is an autosomal dominant heart disease. An induced pluripotent stem cell line (EHTJUi003-A) was generated from umbilical cord blood mononuclear cells (UCBMCs) of a female neonate with heterozygous mutation of p.L460Wfs (c.1377delC) in the MYBPC3 gene. This iPSC model offers a very valuable resource to study the pathological mechanism of HCM in vitro.<br /> (Copyright © 2021. Published by Elsevier B.V.)
Details
- Language :
- English
- ISSN :
- 1876-7753
- Volume :
- 53
- Database :
- MEDLINE
- Journal :
- Stem cell research
- Publication Type :
- Academic Journal
- Accession number :
- 34087980
- Full Text :
- https://doi.org/10.1016/j.scr.2021.102328