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Clinical outcomes of endoprosthetic reconstruction for proximal femoral resection.

Authors :
Kim Y
Jeon DG
Cho WH
Kong CB
Song WS
Source :
Japanese journal of clinical oncology [Jpn J Clin Oncol] 2021 Aug 01; Vol. 51 (8), pp. 1248-1252.
Publication Year :
2021

Abstract

Introduction: The proximal femur is a common site for primary sarcomas and metastatic lesions. Although the early results of tumor prostheses are promising, the long-term results of reconstruction are unknown. The purpose of this study is to evaluate the prognostic factors affecting prosthesis survival and complications after proximal femoral resection and reconstruction.<br />Methods: We reviewed the results of 68 patients who underwent proximal femoral resection and reconstruction with a modular bipolar-type tumor prosthesis between 2005 and 2017. The mean follow-up was 55.6 months (range 6-172 months). There were 50 male and 18 female patients with a mean age of 41.5 years (range 11-80 years). Cumulative survival analysis was performed to analyze the risk factors of prosthesis survival. We also evaluated the complications after operation.<br />Results: Fourteen (21%) patients required further surgery at a mean 37 months post-operatively (range 5-125 months). There were three cases of infection (4%), six of local recurrence (9%), three of acetabular erosion (4%) and two of stem loosening (3%). The implant survival rates were 83.9% at 5 years and 59.8% at 10 years. Prosthesis survivals did not differ based on fixation method (P = 0.085), age (P = 0.329) or resection length (P = 0.61). Acetabular chondrolysis was identified in 18 (26%) patients and longer resection length (≥20 cm) showed a trend for risk of acetabular wear (P = 0.132).<br />Conclusion: The results of proximal femoral resection and reconstruction with a modular bipolar-type prosthesis were found to be acceptable with infection and local recurrence as short-term complications and loosening and acetabular erosion as long-term complications.<br /> (© The Author(s) 2021. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permission@oup.com.)

Details

Language :
English
ISSN :
1465-3621
Volume :
51
Issue :
8
Database :
MEDLINE
Journal :
Japanese journal of clinical oncology
Publication Type :
Academic Journal
Accession number :
34100546
Full Text :
https://doi.org/10.1093/jjco/hyab087