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Hepatitis C Treatment Outcomes in Persons With HIV and Decompensated Cirrhosis Using a Collaborative Multidisciplinary HIV-Centered Approach.
- Source :
-
Journal of the International Association of Providers of AIDS Care [J Int Assoc Provid AIDS Care] 2021 Jan-Dec; Vol. 20, pp. 23259582211024771. - Publication Year :
- 2021
-
Abstract
- Fifty-four consecutive persons with HIV co-infected with hepatitis C virus (HCV) and liver decompensation were treated with direct-acting antivirals (DAA). The HCV treatment was delivered using a multidisciplinary HIV-coinfection model of care integrating sub-specialty services in 3 countries. Of those treated, 91% (95% confidence interval, 80.1 to 95.9) achieved sustained viral response, and only one person died during treatment. Our study provides evidence that HIV providers achieve excellent outcomes when treating patients with histories of decompensated liver disease, with characteristics similar to those studied using a multidisciplinary HIV-centered approach.
- Subjects :
- Antiviral Agents therapeutic use
Hepacivirus
Humans
Liver Cirrhosis complications
Liver Cirrhosis epidemiology
Prospective Studies
Treatment Outcome
Coinfection drug therapy
HIV Infections complications
HIV Infections drug therapy
HIV Infections epidemiology
Hepatitis C complications
Hepatitis C drug therapy
Hepatitis C epidemiology
Hepatitis C, Chronic complications
Hepatitis C, Chronic drug therapy
Hepatitis C, Chronic epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 2325-9582
- Volume :
- 20
- Database :
- MEDLINE
- Journal :
- Journal of the International Association of Providers of AIDS Care
- Publication Type :
- Academic Journal
- Accession number :
- 34132142
- Full Text :
- https://doi.org/10.1177/23259582211024771