Arthritis and enthesitis in the hip and pelvis region in spondyloarthritis - OMERACT validation of two whole-body MRI methods.

Authors :: Wetterslev M
Lambert RG
Maksymowych WP
Eshed I
Pedersen SJ
Bird P
Stoenoiu MS
Krabbe S
Mathew AJ
Foltz V
Gandjbakhch F
Paschke J
De Marco G
Marzo-Ortega H
Carron P
Poulsen AE
Jaremko JL
Conaghan PG
Østergaard M
Source :: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2021 Aug; Vol. 51 (4), pp. 940-945. Date of Electronic Publication: 2021 May 21.
Publication Year :: 2021
Abstract: Objective: To validate reliability, correlation and responsiveness of two whole-body MRI scores for the hip/pelvis region in spondyloarthritis. Methods: Assessment of hip/pelvis inflammation in 4 multi-reader exercises using the OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Hip Inflammation Magnetic Resonance Imaging Scoring System (HIMRISS). Results: In exercises 3-4 (11/20 cases, respectively; 9 readers) reliability was mostly good for the 3 best calibrated readers. Median pairwise single-measure ICC for status were 0.58-0.65 (WIPE-osteitis), 0.10-0.88 (HIMRISS-osteitis) and for status/change 0.38-0.72/0.52-0.60 (WIPE-synovitis/effusion) and 0.68-0.89/0.78-0.85 (HIMRISS-synovitis/effusion). SRM was 1.23 for WIPE-osteitis, while lower for WIPE-synovitis/effusion and HIMRISS. Conclusion: MRI-WIPE and HIMRISS may after further validation be useful in future spondyloarthritis trials. Competing Interests: Declaration of Competing Interest None. (Copyright © 2021 Elsevier Inc. All rights reserved.)

Subjects :: Humans
Magnetic Resonance Imaging
Pelvis
Reproducibility of Results
Severity of Illness Index
Spondylarthritis diagnostic imaging

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