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Childhood dystonic reactions in the middle Black Sea region.
- Source :
-
Medicine [Medicine (Baltimore)] 2021 Jul 02; Vol. 100 (26), pp. e26465. - Publication Year :
- 2021
-
Abstract
- Abstract: Acute dystonic reactions are a worrying reason for presentation to the pediatric emergency department and the pediatric neurology clinic in childhood. It must be diagnosed and treated quickly. The aim of this study was to examine the clinical presentations, etiological factors, and prognosis of patients presenting to our regional tertiary pediatric neurology clinic with a diagnosis of acute dystonic reactions in children.Nine pediatric patients who were treated for acute dystonic reactions between May, 2018 and May, 2020 and had adequate follow-up were included in the study. Medical record data were reviewed age, gender, etiology, features of family, treatment, and results.Three of the patients were female and 6 were male. Their average age was 11 years (4-17). All patients were evaluated as a drug-induced acute dystonic reaction. Of the 9 patients, 5 were due to metoclopramide, 3 were due to risperidone, and 1 was due to aripiprazole. It was learned that a similar situation against other drugs developed in the family history of 3 patients. As a treatment, all of them were intramuscularly applied biperiden suitable for their weight and 30 minutes dramatic improvement was observed. Additional dose had to be administered in only 1 case. All cases were discharged for 24 hours. No problem was observed in their follow-up.Drug-induced acute dystonic reaction can be diagnosed and has a clinical picture that completely resolves when effective treatment is applied. However, it should not be forgotten that it can reach life-threatening dimensions clinically.<br />Competing Interests: The author has no funding and conflicts of interest to disclose.<br /> (Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Age of Onset
Antipsychotic Agents administration & dosage
Antipsychotic Agents adverse effects
Aripiprazole administration & dosage
Child
Disease Susceptibility
Dopamine D2 Receptor Antagonists administration & dosage
Dopamine D2 Receptor Antagonists adverse effects
Female
Humans
Injections, Intramuscular
Male
Medical History Taking
Metoclopramide administration & dosage
Parasympatholytics administration & dosage
Risperidone administration & dosage
Treatment Outcome
Turkey epidemiology
Aripiprazole adverse effects
Biperiden administration & dosage
Dystonia chemically induced
Dystonia diagnosis
Dystonia drug therapy
Dystonia epidemiology
Metoclopramide adverse effects
Risperidone adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 100
- Issue :
- 26
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 34190170
- Full Text :
- https://doi.org/10.1097/MD.0000000000026465