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Predictors of Nonseroconversion after SARS-CoV-2 Infection.

Authors :
Liu W
Russell RM
Bibollet-Ruche F
Skelly AN
Sherrill-Mix S
Freeman DA
Stoltz R
Lindemuth E
Lee FH
Sterrett S
Bar KJ
Erdmann N
Gouma S
Hensley SE
Ketas T
Cupo A
Cruz Portillo VM
Moore JP
Bieniasz PD
Hatziioannou T
Massey G
Minyard MB
Saag MS
Davis RS
Shaw GM
Britt WJ
Leal SM Jr
Goepfert P
Hahn BH
Source :
Emerging infectious diseases [Emerg Infect Dis] 2021 Sep; Vol. 27 (9), pp. 2454-2458. Date of Electronic Publication: 2021 Jun 30.
Publication Year :
2021

Abstract

Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2-specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response.

Details

Language :
English
ISSN :
1080-6059
Volume :
27
Issue :
9
Database :
MEDLINE
Journal :
Emerging infectious diseases
Publication Type :
Academic Journal
Accession number :
34193339
Full Text :
https://doi.org/10.3201/eid2709.211042