First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients With COVID-19.

Authors :: Tantry US
Bliden KP
Cho A
Walia N
Dahlen JR
Ens G
Traianova M
Jerjian C
Usman A
Gurbel PA
Source :: Open forum infectious diseases [Open Forum Infect Dis] 2021 May 26; Vol. 8 (7), pp. ofab274. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Urine 11-dehydro-thromboxane B <subscript>2</subscript> (u11-dh-TxB <subscript>2</subscript> ), 8-hydroxy-2'-deoxyguanosine (8-OHdG), and liver-type fatty acid binding protein levels (L-FABP) at the time of hospitalization were higher in coronavirus disease 2019 (COVID-19) patients with adverse events vs without events. Higher u11-dh-TxB <subscript>2</subscript> and L-FABP levels were associated with longer hospitalization, more thrombotic events, and greater mortality, providing evidence for potential utility as early prognostic biomarkers for COVID-19.<br /> (© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

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