Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment.

Authors :: Wong TH
Ambinder D
Flusberg M
Shakil F
Phillips JL
Wong NC
Source :: Urology case reports [Urol Case Rep] 2021 Jul 09; Vol. 39, pp. 101775. Date of Electronic Publication: 2021 Jul 09 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.<br />Competing Interests: None.<br /> (© 2021 Published by Elsevier Inc.)

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