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Replenishing our mind orchards: Enhancing myelin renewal to rescue cognition in Alzheimer's disease.

Authors :
McNamara NB
Miron VE
Source :
Neuron [Neuron] 2021 Jul 21; Vol. 109 (14), pp. 2204-2206.
Publication Year :
2021

Abstract

In this issue of Neuron, Chen et al. (2021) reveal dynamic changes in myelin in an Alzheimer's disease (AD) mouse model. Enhancing myelination genetically or pharmacologically improves cognition in this model, supporting myelin as a therapeutic target for AD.<br />Competing Interests: Declaration of interests V.E.M. has received consultancy funds from Novartis and Biogen and research funds from Biogen, Clene Nanomedicine, ReWind Therapeutics, and GSK.<br /> (Copyright © 2021 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4199
Volume :
109
Issue :
14
Database :
MEDLINE
Journal :
Neuron
Publication Type :
Academic Journal
Accession number :
34293288
Full Text :
https://doi.org/10.1016/j.neuron.2021.06.024