Back to Search
Start Over
Screening-based identification of xanthone as a novel NLRP3 inflammasome inhibitor via metabolic reprogramming.
- Source :
-
Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e496. - Publication Year :
- 2021
- Subjects :
- Adenosine Triphosphate pharmacology
Animals
Humans
Interleukin-1beta metabolism
Keratitis drug therapy
Keratitis pathology
Keratitis veterinary
Leukocytes, Mononuclear cytology
Leukocytes, Mononuclear drug effects
Leukocytes, Mononuclear metabolism
Lipopolysaccharides pharmacology
Macrophages cytology
Macrophages metabolism
Mice
Mitochondrial Dynamics drug effects
NLR Family, Pyrin Domain-Containing 3 Protein antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein genetics
Xanthones therapeutic use
Inflammasomes metabolism
NLR Family, Pyrin Domain-Containing 3 Protein metabolism
Xanthones pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 2001-1326
- Volume :
- 11
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Clinical and translational medicine
- Publication Type :
- Report
- Accession number :
- 34323410
- Full Text :
- https://doi.org/10.1002/ctm2.496