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The Nationwide Incidence of Retinal Vein Occlusion Following Dialysis due to End-stage Renal Disease in Korea, 2004 through 2013.
- Source :
-
Journal of Korean medical science [J Korean Med Sci] 2021 Aug 02; Vol. 36 (30), pp. e201. Date of Electronic Publication: 2021 Aug 02. - Publication Year :
- 2021
-
Abstract
- Background: We investigated the incidence and risk of retinal vein occlusion (RVO) in end-stage renal disease (ESRD) patients on dialysis in Korea.<br />Methods: In this nationwide cohort study, we used Korean National Health Insurance Service data between 2004 and 2013 for analysis. ESRD patients who started dialysis from 2004 to 2013 and an equal number of controls were selected through propensity score matching. RVO incidence in both cohorts were calculated for 2004-2013 using washout data from 2003. The multivariable Cox proportional hazards model was used to assess the risk of RVO in dialysis cohort. The Kaplan-Meier method was used to generate the cumulative RVO incidence curve. Whether the dialysis modality affects the development of RVO was also evaluated.<br />Results: In this study, 74,551 ESRD patients on dialysis and the same number of controls were included. The incidence of RVO was significantly higher in the dialysis cohort than in the control cohort (dialysis = 7.3/1,000 person-years [PY]; control = 1.9/1,000 PY; P < 0.001). The cumulative-incidence of RVO was also significantly higher in the dialysis cohort than in the control cohort ( P < 0.001; log-rank test). However, there was no significant difference in the incidence of RVO between the two dialysis methods ( P = 0.550; log-rank test).<br />Conclusion: This study provided epidemiological evidence that receiving dialysis for ESRD could increase the risk of developing RVO. We also found a rapid increase in the incidence of RVO with a longer dialysis period. These results strengthen the relationship between retinal vascular disease and renal function.<br />Competing Interests: The authors have no potential conflicts of interest to disclose.<br /> (© 2021 The Korean Academy of Medical Sciences.)
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Case-Control Studies
Child
Child, Preschool
Cohort Studies
Female
Humans
Incidence
Infant
Infant, Newborn
Kaplan-Meier Estimate
Kidney Failure, Chronic complications
Male
Middle Aged
Republic of Korea epidemiology
Retinal Vein Occlusion etiology
Retrospective Studies
Risk Factors
Kidney Failure, Chronic therapy
Renal Dialysis adverse effects
Retinal Vein Occlusion epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1598-6357
- Volume :
- 36
- Issue :
- 30
- Database :
- MEDLINE
- Journal :
- Journal of Korean medical science
- Publication Type :
- Academic Journal
- Accession number :
- 34342186
- Full Text :
- https://doi.org/10.3346/jkms.2021.36.e201