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Randomised controlled trial and economic evaluation of a targeted cancer awareness intervention for adults living in deprived areas of the UK.
- Source :
-
British journal of cancer [Br J Cancer] 2021 Oct; Vol. 125 (8), pp. 1100-1110. Date of Electronic Publication: 2021 Aug 27. - Publication Year :
- 2021
-
Abstract
- Background: Cancer outcomes are poor in socioeconomically deprived communities, with low symptom awareness contributing to prolonged help-seeking and advanced disease. Targeted cancer awareness interventions require evaluation.<br />Methods: This is a randomised controlled trial involving adults aged 40+ years recruited in community and healthcare settings in deprived areas of South Yorkshire and South-East Wales.<br />Intervention: personalised behavioural advice facilitated by a trained lay advisor.<br />Control: usual care. Follow-up at two weeks and six months post-randomisation.<br />Primary Outcome: total cancer symptom recognition score two weeks post-randomisation.<br />Results: Two hundred and thirty-four participants were randomised. The difference in total symptom recognition at two weeks [adjusted mean difference (AMD) 0.6, 95% CI: -0.03, 1.17, p = 0.06] was not statistically significant. Intervention participants reported increased symptom recognition (AMD 0.8, 95% CI: 0.18, 1.37, p = 0.01) and earlier intended presentation (AMD -2.0, 95% CI: -3.02, -0.91, p < 0.001) at six months. "Lesser known" symptom recognition was higher in the intervention arm (2 weeks AMD 0.5, 95% CI: 0.03, 0.97 and six months AMD 0.7, 95% CI: 0.16, 1.17). Implementation cost per participant was £91.34, with no significant between-group differences in healthcare resource use post-intervention.<br />Conclusions: Improved symptom recognition and earlier anticipated presentation occurred at longer-term follow-up. The ABACus Health Check is a viable low-cost intervention to increase cancer awareness in socioeconomically deprived communities.<br />Clinical Trial Registration: ISRCTN16872545.<br /> (© 2021. The Author(s).)
Details
- Language :
- English
- ISSN :
- 1532-1827
- Volume :
- 125
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- British journal of cancer
- Publication Type :
- Academic Journal
- Accession number :
- 34453114
- Full Text :
- https://doi.org/10.1038/s41416-021-01524-5