Molecular Management of Multifocal Atrial Tachycardia in Noonan's Syndrome With MEK1/2 Inhibitor Trametinib.

Authors :: Meisner JK
Bradley DJ
Russell MW
Source :: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2021 Oct; Vol. 14 (5), pp. e003327. Date of Electronic Publication: 2021 Aug 31.
Publication Year :: 2021

Subjects :: Female
Humans
Infant, Newborn
MAP Kinase Kinase 1 genetics
MAP Kinase Kinase 2 genetics
MAP Kinase Kinase 1 antagonists & inhibitors
MAP Kinase Kinase 2 antagonists & inhibitors
Noonan Syndrome drug therapy
Noonan Syndrome enzymology
Noonan Syndrome genetics
Point Mutation
Proto-Oncogene Proteins c-raf genetics
Pyridones administration & dosage
Pyrimidinones administration & dosage
Tachycardia drug therapy
Tachycardia enzymology
Tachycardia genetics

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