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Risk Factors for Complications Associated with Peripherally Inserted Central Catheters During Induction Chemotherapy for Acute Myeloid Leukemia.
- Source :
-
Internal medicine (Tokyo, Japan) [Intern Med] 2022 Apr 01; Vol. 61 (7), pp. 989-995. Date of Electronic Publication: 2021 Sep 11. - Publication Year :
- 2022
-
Abstract
- Objective Peripherally inserted central catheters (PICCs) are widely used in patients with hematologic malignancies. However, the risks of PICC-related complications during chemotherapy for acute myeloid leukemia (AML) are not fully understood. Methods We conducted a retrospective review of 128 adult patients with AML who received induction therapy by way of PICC insertion between 2012 and 2019. Results The median duration of PICC insertion was 30 days. The incidence rate of catheter-related bloodstream infection (CRBSI) was 2.4% at 30 days, and women were more likely to suffer from CRBSI than men. Local reactions at the insertion site were observed in 56 patients; however, these events did not predict CRBSI. The incidence rates of catheter-related thrombosis (CRT) were 1.6% at 30 days. Obesity put patients at an increased risk for CRT. Unexpected PICC removal occurred in 59 patients, and women were at a higher risk of catheter removal than men. Conclusion Low PICC-related complication rates, possibly associated with high rates of catheter removal, were observed during intensive chemotherapy for AML. Women and obese patients require careful monitoring of their PICC. Procedures to achieve appropriate PICC removal without increasing the complication rate need to be considered.
- Subjects :
- Adult
Catheters adverse effects
Female
Humans
Induction Chemotherapy adverse effects
Male
Retrospective Studies
Risk Factors
Catheter-Related Infections epidemiology
Catheter-Related Infections etiology
Catheterization, Central Venous adverse effects
Catheterization, Peripheral adverse effects
Central Venous Catheters adverse effects
Leukemia, Myeloid, Acute complications
Leukemia, Myeloid, Acute epidemiology
Leukemia, Myeloid, Acute therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1349-7235
- Volume :
- 61
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Internal medicine (Tokyo, Japan)
- Publication Type :
- Academic Journal
- Accession number :
- 34511570
- Full Text :
- https://doi.org/10.2169/internalmedicine.8184-21