Relapsed Babesia microti Infection Following Allogeneic Hematopoietic Cell Transplantation in a Patient With B-cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.

Authors :: Rosenblatt J
Leung A
Baneman E
Fuller R
Taimur S
Paniz-Mondolfi AE
Malone AK
Kirkman L
Jacobs SE
Source :: Open forum infectious diseases [Open Forum Infect Dis] 2021 Jun 21; Vol. 8 (9), pp. ofab323. Date of Electronic Publication: 2021 Jun 21 (Print Publication: 2021).
Publication Year :: 2021
Abstract: A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis before allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole-blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.<br /> (© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

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