Lasibidoupins A and B, two new compounds from the stems of Lasianthus bidoupensis V.S. Dang & Naiki.

From the Lasianthus bidoupensis stems, two new compounds, including one new 9,10-anthraquinone, lasibidoupin A ( 1 ), and one new 6,7-benzocoumarin, lasibidoupin B ( 2 ), together with one known compound, 11- O -methyldamnacanthol ( 3 ) were isolated using chromatographic method. Their structures were determined by extensive HRMS, and NMR assignments. Compound 3 was reported for the first time from this species. New compounds ( 1 & 2 ) were tested for the cytotoxicity against three human cancer cell lines (MCF-7, HeLa, and NCI-H460) by SRB assay. As results, 1 & 2 exhibited significant cytotoxic activity against all cancer cell lines (IC ₅₀ ranged from 0.058   ± 0.003 to 0.177 ± 0.014 μM).