Back to Search
Start Over
Sublingual microcirculation predicts survival after out-of-hospital cardiac arrest.
- Source :
-
Microcirculation (New York, N.Y. : 1994) [Microcirculation] 2021 Nov; Vol. 28 (8), pp. e12729. Date of Electronic Publication: 2021 Oct 26. - Publication Year :
- 2021
-
Abstract
- Background: Despite successful resuscitation with return of spontaneous circulation (ROSC), the prediction of survival in patients suffering out-of-hospital cardiac arrest (OHCA) remains difficult. Several studies have shown alterations in sublingual microcirculation in the critical ill. We hypothesized that early alterations in sublingual microcirculation may predict short-term survival after OHCA.<br />Methods: We prospectively included all adults admitted to our university hospital between April and September 2019 with ROSC following OHCA. Sidestream dark-field microscopy to obtain sublingual microcirculation was performed at admission and after 6, 12 and 24 hours. Primary outcome was survival until discharge.<br />Results: Twenty-five patients were included. Six hours after ROSC, the proportion of perfused small vessels (PPV <subscript>small</subscript> ) was lower in non-survivors than in survivors (85 ± 7.9 vs. 75 ± 6.6%; p = .01). PPV <subscript>small</subscript> did not correlate with serum lactate. Stratification for survival with cutoff values >78.4% for PPV <subscript>small</subscript> 6 h post-admission and <5.15 mmol/l for initial serum lactate as suggested by ROC-Analyses results in a positive predictive value of 100% and a negative one of 67% for our study population.<br />Conclusion: Estimating short-term prognosis of OHCA patients with ROSC may be supported by measuring the PPV <subscript>small</subscript> at the sublingual microcirculation 6 hours after admission.<br /> (© 2021 The Authors. Microcirculation published by John Wiley & Sons Ltd.)
Details
- Language :
- English
- ISSN :
- 1549-8719
- Volume :
- 28
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Microcirculation (New York, N.Y. : 1994)
- Publication Type :
- Academic Journal
- Accession number :
- 34564926
- Full Text :
- https://doi.org/10.1111/micc.12729