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Better health-related quality of life in kidney transplant patients compared to chronic kidney disease patients with similar renal function.
- Source :
-
PloS one [PLoS One] 2021 Oct 04; Vol. 16 (10), pp. e0257981. Date of Electronic Publication: 2021 Oct 04 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Renal functional deterioration is associated with physical and mental burdens for kidney transplant (KT) and chronic kidney disease (CKD) patients. However, the change in health-related quality of life (HRQOL) over time in KT patients compared to that of native CKD patients has not been evaluated. We addressed this issue using KT patients registered in the KNOW-KT cohort study and patients at CKD stage 1-3 registered in the KNOW-CKD cohort study. HRQOL scores were assessed using the Kidney Disease Quality of Life Short Form at baseline, 2-, and 4-years follow-up in 842 KT patients and at baseline and 5-year follow-up in 1,355 CKD patients. SF-36 scores declined at the 4-year follow-up, whereas CKD-targeted scores showed no change in the KT group. In contrast, CKD-targeted scores as well as SF-36 scores were decreased at the 5-year follow-up in CKD patients. When prognostic factors were analyzed for longitudinal HRQOL data over time, renal functions, diabetes, cardiovascular and cerebrovascular diseases, hemoglobin level, marital status, income, employment, and health care were significant prognostic factors. Furthermore, KT was an independent prognostic factor for better HRQOL. These results highlight that KT can offer a better HRQOL than that of CKD patients, even when renal function is similar.<br />Competing Interests: The authors have declared that no competing interests exist.
- Subjects :
- Adult
Aged
Comorbidity
Delivery of Health Care
Employment
Female
Follow-Up Studies
Hemoglobins analysis
Humans
Income
Longitudinal Studies
Male
Marital Status
Middle Aged
Prognosis
Renal Insufficiency, Chronic blood
Seoul epidemiology
Cerebrovascular Disorders epidemiology
Diabetes Mellitus epidemiology
Kidney physiopathology
Kidney Transplantation
Quality of Life
Renal Insufficiency, Chronic epidemiology
Renal Insufficiency, Chronic physiopathology
Transplant Recipients
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 16
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 34606505
- Full Text :
- https://doi.org/10.1371/journal.pone.0257981