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Retroperitoneal Fibrosis: Beware of Lymphoma.
- Source :
-
Cureus [Cureus] 2021 Aug 31; Vol. 13 (8), pp. e17587. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Retroperitoneal fibrosis is a rare disease manifesting as chronic soft tissue fibrosis in the retroperitoneum, with potential anatomic and/or functional compromise of adjacent organs. It can be primary (idiopathic) or secondary to other conditions such as cancers, radiotherapy, surgery, traumatisms, infections, autoimmune disorders, or drugs. We report herein a 54-year-old patient with symptomatic retroperitoneal fibrosis leading to bilateral hydronephrosis and renal failure, in whom, after a complex diagnostic workup and protracted clinical course, a follicular lymphoma in the retroperitoneal was identified. The patient was treated with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy protocol, with a resolution of hydronephrosis and lower back pain. We include a thorough literature review on etiopathogenesis, diagnosis, therapy, and prognosis of retroperitoneal fibrosis. A meticulous search for malignancy is necessary for this rare condition that, if positive, may have significant therapeutic and prognostic implications.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2021, Ouchani et al.)
Details
- Language :
- English
- ISSN :
- 2168-8184
- Volume :
- 13
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Cureus
- Publication Type :
- Report
- Accession number :
- 34646640
- Full Text :
- https://doi.org/10.7759/cureus.17587