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Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions.
- Source :
-
Cytometry. Part A : the journal of the International Society for Analytical Cytology [Cytometry A] 2022 Feb; Vol. 101 (2), pp. 131-139. Date of Electronic Publication: 2021 Oct 18. - Publication Year :
- 2022
-
Abstract
- The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.<br /> (© 2021 The Authors. Cytometry Part A published by Wiley Periodicals LLC. on behalf of International Society for Advancement of Cytometry.)
- Subjects :
- Flow Cytometry
Humans
Phenotype
B-Lymphocytes
Subjects
Details
- Language :
- English
- ISSN :
- 1552-4930
- Volume :
- 101
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cytometry. Part A : the journal of the International Society for Analytical Cytology
- Publication Type :
- Academic Journal
- Accession number :
- 34664397
- Full Text :
- https://doi.org/10.1002/cyto.a.24507