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Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions.

Authors :
Carsetti R
Terreri S
Conti MG
Fernandez Salinas A
Corrente F
Capponi C
Albano C
Piano Mortari E
Source :
Cytometry. Part A : the journal of the International Society for Analytical Cytology [Cytometry A] 2022 Feb; Vol. 101 (2), pp. 131-139. Date of Electronic Publication: 2021 Oct 18.
Publication Year :
2022

Abstract

The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.<br /> (© 2021 The Authors. Cytometry Part A published by Wiley Periodicals LLC. on behalf of International Society for Advancement of Cytometry.)

Details

Language :
English
ISSN :
1552-4930
Volume :
101
Issue :
2
Database :
MEDLINE
Journal :
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Publication Type :
Academic Journal
Accession number :
34664397
Full Text :
https://doi.org/10.1002/cyto.a.24507