Identification of recurrent genomic alterations in the apoptotic machinery in chronic lymphocytic leukemia patients treated with venetoclax monotherapy.

Authors :: Popovic R
Dunbar F
Lu C
Robinson K
Quarless D
Warder SE
Mukherjee N
Pesko J
Souers AJ
Waring JF
Davids MS
Tausch E
Stilgenbauer S
Ross JA
Leverson JD
Kim SY
Chyla BJ
Source :: American journal of hematology [Am J Hematol] 2022 Feb 01; Vol. 97 (2), pp. E47-E51. Date of Electronic Publication: 2021 Nov 24.
Publication Year :: 2022

Subjects :: Antineoplastic Agents pharmacology
Bridged Bicyclo Compounds, Heterocyclic pharmacology
Cell Line, Tumor
Drug Resistance, Neoplasm
Gene Expression Regulation, Leukemic drug effects
Humans
Leukemia, Lymphocytic, Chronic, B-Cell genetics
Mutation drug effects
Sulfonamides pharmacology
Antineoplastic Agents therapeutic use
Apoptosis drug effects
Bridged Bicyclo Compounds, Heterocyclic therapeutic use
Leukemia, Lymphocytic, Chronic, B-Cell drug therapy
Sulfonamides therapeutic use

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