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Glucose oxidase@zinc-doped zeolitic imidazolate framework-67 as an effective cascade catalyst for one-step chemiluminescence sensing of glucose.
- Source :
-
Mikrochimica acta [Mikrochim Acta] 2021 Nov 23; Vol. 188 (12), pp. 427. Date of Electronic Publication: 2021 Nov 23. - Publication Year :
- 2021
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Abstract
- A chemiluminescence (CL) sensor was constructed for the one-step determination of glucose. Glucose oxidase (GOx) was successfully encapsulated into Zn-doped zeolitic imidazolate framework-67 (Zn-ZIF-67) via a simple one-pot strategy. The as-prepared GOx@Zn-ZIF-67 nanocomposite can trigger cascade reactions of glucose oxidation to generate H <subscript>2</subscript> O <subscript>2</subscript> and H <subscript>2</subscript> O <subscript>2</subscript> -mediated luminol reaction to give an intense CL emission. The sensor responds linearly to glucose in the 20.0-400.0 μmol·L <superscript>-1</superscript> range with a limit of detection (LOD) of 4.7 μmol·L <superscript>-1</superscript> . Eleven replicated measurements of 200.0 μmol·L <superscript>-1</superscript> glucose solution gives a relative standard deviation (RSD) of 1.7%. The sensor exhibits good selectivity and stability and was successfully applied to the determination of glucose in real human serum samples. Schematic representation of one-step determination of serum glucose with GOx@Zn-ZIF-67 nanocomposite triggering cascade reactions between luminol and glucose.<br /> (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
Details
- Language :
- English
- ISSN :
- 1436-5073
- Volume :
- 188
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Mikrochimica acta
- Publication Type :
- Academic Journal
- Accession number :
- 34812945
- Full Text :
- https://doi.org/10.1007/s00604-021-05096-2