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Glycine Transporters and Receptors as Targets for Analgesics.

Authors :
Harvey RJ
Vandenberg RJ
Source :
Biomolecules [Biomolecules] 2021 Nov 11; Vol. 11 (11). Date of Electronic Publication: 2021 Nov 11.
Publication Year :
2021

Abstract

The suitability of modulating glycinergic neurotransmission for the treatment of inflammatory and chronic pain has gained widespread recognition, with glycine receptors (GlyRs) and glycine transporters (GlyT1 and GlyT2) now considered key therapeutic targets [...].

Subjects

Subjects :
Analgesics pharmacology
Glycine
Receptors, Glycine genetics
Glycine Plasma Membrane Transport Proteins genetics
Glycine Plasma Membrane Transport Proteins metabolism
Synaptic Transmission

Details

Language :
English
ISSN :
2218-273X
Volume :
11
Issue :
11
Database :
MEDLINE
Journal :
Biomolecules
Publication Type :
Editorial & Opinion
Accession number :
34827674
Full Text :
https://doi.org/10.3390/biom11111676
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