Identification of TMB, CD8 T-cell abundance, and homologous repair pathway mutation frequency as predictors of the benefit-toxicity ratio of anti-PD-1/PD-L1 therapy.

Subjects

Subjects :

B7-H1 Antigen therapeutic use
CD8-Positive T-Lymphocytes immunology
Humans
Leukocyte Count methods
B7-H1 Antigen adverse effects
CD8-Positive T-Lymphocytes classification
Leukocyte Count statistics & numerical data
Programmed Cell Death 1 Receptor metabolism

Details

Language :

English

ISSN :

2001-1326

Volume :

11

Issue :

11

Database :

MEDLINE

Journal :

Clinical and translational medicine

Publication Type :

Report

Accession number :

34841682

Full Text :

https://doi.org/10.1002/ctm2.598