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Effect of surgical treatment on prognosis in preterm infants with obstructive hydrocephalus.

Authors :
Liu YF
Huang CL
Tong XM
Zhang Y
Zeng L
Yuan JF
Source :
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics [Zhongguo Dang Dai Er Ke Za Zhi] 2021 Dec 15; Vol. 23 (12), pp. 1214-1220.
Publication Year :
2021

Abstract

Objectives: To study the effect of surgical treatment on prognosis in preterm infants with obstructive hydrocephalus.<br />Methods: A retrospective analysis was performed on the medical data of 49 preterm infants with obstructive hydrocephalus. According to the treatment regimen, they were divided into two groups: surgical treatment ( n =12) and conservative treatment ( n =37). The drainage methods, drainage complications, and eventual shunt outcome were analyzed in the surgical treatment group. The two groups were compared in terms of the etiology of hydrocephalus and prognosis.<br />Results: Among the 49 preterm infants with obstructive hydrocephalus, severe intracranial hemorrhage (37 cases; 76%) and central nervous system infection (10 cases, 20%) were the main causes of hydrocephalus. There was no significant difference in the composition of etiology between the two groups ( P >0.05). In the surgical treatment group, 4 infants were treated with ventriculosubgaleal shunt and 8 were treated with Ommaya reservoir. One infant had secondary infection and 8 infants eventually underwent ventriculoperitoneal shunt. The surgical treatment group had a significantly higher survival rate than the conservative treatment group ( P <0.05). As for the 37 preterm infants with severe intracranial hemorrhage, the surgical treatment group had a significantly higher proportion of infants with normal neurodevelopment than the conservative treatment group ( P <0.05). As for the 10 preterm infants with central nervous system infection, neurodevelopmental abnormalities were observed in each of the two groups.<br />Conclusions: Surgical treatment can improve the survival rate of preterm infants with obstructive hydrocephalus and the prognosis of preterm infants with severe intracranial hemorrhage.

Details

Language :
English; Chinese
ISSN :
1008-8830
Volume :
23
Issue :
12
Database :
MEDLINE
Journal :
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Publication Type :
Academic Journal
Accession number :
34911603
Full Text :
https://doi.org/10.7499/j.issn.1008-8830.2108119