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Lonomia obliqua Envenoming and Innovative Research.

Authors :
Alvarez-Flores MP
Gomes RN
Trevisan-Silva D
Oliveira DS
Batista IFC
Buri MV
Alvarez AM
DeOcesano-Pereira C
de Souza MM
Chudzinski-Tavassi AM
Source :
Toxins [Toxins (Basel)] 2021 Nov 23; Vol. 13 (12). Date of Electronic Publication: 2021 Nov 23.
Publication Year :
2021

Abstract

As a tribute to Butantan Institute in its 120th anniversary, this review describes some of the scientific research efforts carried out in the study of Lonomia envenoming in Brazil, a country where accidents with caterpillars reach over 42,000 individuals per year (especially in South and Southeast Brazil). Thus, the promising data regarding the studies with Lonomia 's toxins contributed to the creation of new research centers specialized in toxinology based at Butantan Institute, as well as to the production of the antilonomic serum (ALS), actions which are in line with the Butantan Institute mission "to research, develop, manufacture, and provide products and services for the health of the population". In addition, the study of the components of the Lonomia obliqua bristle extract led to the discovery of new molecules with peculiar properties, opening a field of knowledge that could lead to the development and innovation of new drugs aimed at cell regeneration and inflammatory diseases.

Details

Language :
English
ISSN :
2072-6651
Volume :
13
Issue :
12
Database :
MEDLINE
Journal :
Toxins
Publication Type :
Academic Journal
Accession number :
34941670
Full Text :
https://doi.org/10.3390/toxins13120832