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MicroRNAs: Potential biomarkers for reproduction, diagnosis, prognosis, and therapeutic in domestic animals.

Authors :
Winter E
Cisilotto J
Silva AH
Rosolen D
Fabichak AP
Rode MP
Creczynski-Pasa TB
Source :
Research in veterinary science [Res Vet Sci] 2021 Dec 07; Vol. 142, pp. 117-132. Date of Electronic Publication: 2021 Dec 07.
Publication Year :
2021
Publisher :
Ahead of Print

Abstract

MicroRNA (miRNAs) are small non-coding RNA molecules involved in a wide range of biological processes through the post-transcriptional regulation of gene expression. Most studies evaluated microRNA expression in human, and despite fewer studies in veterinary medicine, this topic is one of the most exciting areas of modern veterinary medicine. miRNAs showed to be part of the pathogenesis of diseases and reproduction physiology in animals, making them biomarkers candidates. This review provides an overview of the current knowledge regarding miRNAs' role in reproduction and animal diseases, diagnostic and therapy.<br /> (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1532-2661
Volume :
142
Database :
MEDLINE
Journal :
Research in veterinary science
Publication Type :
Academic Journal
Accession number :
34942556
Full Text :
https://doi.org/10.1016/j.rvsc.2021.12.004