Cycloserine did not increase depression incidence or severity at standard dosing for multidrug-resistant tuberculosis.

Competing Interests: Conflict of interest: J.A. Tornheim reports, during the conduct of the study, salary support from NIH/NIAID (K23AI135102, R21AI122922 and R01AI134430), salary support from the NIH Fogarty International Center (R25TW009340) and salary support from the Johns Hopkins Clinician Scientist Career Development Award; salary support for a study clinician during the first year of the project was provided by the Frederick Mulder Foundation and the Pogge Tong Foundation. C. Rodrigues reports payment for manuscript writing, honoraria for lectures, educational events from Pfizer; honoraria for lectures from Cipla, Glenmark and Novartis; outside the submitted work. All other authors have nothing to disclose.