Biomanufacturing in low Earth orbit for regenerative medicine.

Authors :: Sharma A
Clemens RA
Garcia O
Taylor DL
Wagner NL
Shepard KA
Gupta A
Malany S
Grodzinsky AJ
Kearns-Jonker M
Mair DB
Kim DH
Roberts MS
Loring JF
Hu J
Warren LE
Eenmaa S
Bozada J
Paljug E
Roth M
Taylor DP
Rodrigue G
Cantini P
Smith AW
Giulianotti MA
Wagner WR
Source :: Stem cell reports [Stem Cell Reports] 2022 Jan 11; Vol. 17 (1), pp. 1-13. Date of Electronic Publication: 2021 Dec 30.
Publication Year :: 2022
Abstract: Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space.<br /> (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)