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Puerarin-an isoflavone with beneficial effects on bone health.

Authors :
Kulczyński B
Gramza-Michałowska A
Suliburska J
Sidor A
Source :
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2021 Dec 30; Vol. 26 (12), pp. 1653-1667.
Publication Year :
2021

Abstract

Puerarin is a compound from the group of isoflavones, naturally occurring in plants of the genus Pueraria, whose representatives include, among others, Pueraria lobata and Pueraria mirifica. Relatively many scientific studies on the biological activity of puerarin have been conducted so far. It seems that most attention was paid to the effect of puerarin on bone health. However, until now, no published studies have been collected and discussed in that regard. Based on the available data obtained from in vitro studies and on the animal model, it can be clearly shown that puerarin is an effective compound in inhibiting bone resorption and improving bone structure. Consumption of puerarin may be associated with the prevention of bone mass loss and thus can reduce the risk of developing osteoporosis. However, it is necessary to conduct human intervention studies to confirm the effectiveness of such action.<br /> (© 2021 The Author(s). Published by BRI.)

Details

Language :
English
ISSN :
2768-6698
Volume :
26
Issue :
12
Database :
MEDLINE
Journal :
Frontiers in bioscience (Landmark edition)
Publication Type :
Academic Journal
Accession number :
34994179
Full Text :
https://doi.org/10.52586/5058